Document Type : Original Article
Authors
1 MSc, Computer Engineering, Department of Software, School of Computer Engineering, Iran University of Science and Technology, Tehran, Iran
2 BSc, Computer Engineering, Department of Artificial Intelligence and Robotics, School of Computer Engineering, Iran University of Science and Technology, Tehran, Iran
3 Assistant Professor, Computer Engineering, Department of Software, School of Computer Engineering, Iran University of Science and Technology, Tehran, Iran
Abstract
Introduction: In recent years, the infertility ratio in young couples has been increased a lot in Iran. From the other side, it has been shown that data mining techniques are capable of extracting novel patterns from medical data. In this study, we proposed a comprehensive system called Prediction of the best Infertility treatment using Outlier Detection and Ensemble Methods (PIODEM) for predicting of the best infertility treatment method for infertile couples.Methods: This descriptive-correlation study used the information of 527 infertile couples, which collected from Avicenna specialized infertility center, Tehran, Iran. PIODEM consists of three steps: First, PIODEM uses the discriminant analysis to find effective factors for choosing the best infertility treatment. Second, PIODEM detects the outlier samples, and applies a correlation between these samples and the choice of treatment method. Third, it uses ensemble methods to increase the precision of classifiers.Results: The PIODEM system succeeded in discovering affective factors such as male-partner’s age, infertility duration, immotile sperm, decreasing of sperm concentration decrease, total sperm count, morphology, sperm motility, sperm with rapid progressive-a motility, and sperm with slow progressive-b motility. Additionally, PIODEM indicates that if one of four features of sperm concentration, toxoplasma immunoglobulin M (IgM), triiodothyronine (T3) hormone, and thyroid peroxidase (TPO) was an outlier, then the prediction of treatment would be more accurate. Finally, using ensemble methods increased the F-measure of PIODEM system by up to 76%.Conclusion: The PIODEM system is able to discover effective factors in the choice of treatment method, using differential analysis and analysis of pert data. This system offers patient information as input for the treatment method.
Keywords
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